Prof Terence Kee Yi Shern

Designation

Senior Consultant Renal Physician Clinical Professor, Duke-NUS Medical School

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Institution

Singapore General Hospital

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Qualification

• MBBS (Australia) 1995
• MRCP (Edinburgh) 2000
• FAMS (Renal Medicine) 2004
• FRCP (Edinburgh) 2011

FASN (USA) 2012

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Special field of interest

Renal, Pancreas and Uterus Transplantation

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Abstract

Title:

The Role of Antibodies in Antibody Mediated Rejection

Body:

Antibody mediated rejection is an important cause of graft loss but effective treatments to improve graft prognosis remain lacking. However, recent years have seen the emergence of gene transcript analysis, cell free DNA and specific therapeutics for plasma cells and NK cells to improve the diagnosis and treatment of antibody mediated rejection. The future for antibody mediated rejection management is exciting as we approach the condition with multimodal diagnostics and therapeutics. Challenges remain due to their high costs and the need to sustain such treatments over a long period of time to prevent rebound rejection.